Tapentadol 200 mg is manufactured by several pharmaceutical companies, primarily as a generic version of the brand-name Nucynta. Notable manufacturers include Intas Pharmaceuticals, Cipla, Sun Pharma, Zydus Cadila, and Lupin Laboratories. These companies produce immediate-release and extended-release formulations, ensuring wide availability in both domestic and international markets. Always check the manufacturer label for authenticity and consult your pharmacist for the best quality option available.